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Structural and functional visualization diagnostics

The modern high-resolution visualization diagnostics plays the vital role in determining the brain area where the epileptic seizures are developed and in defining the reasons of seizures in case of focal epilepsy. Besides that there are more and more opportunities for brain functions mapping by means of functional image transmission.

Over the recent years the structural and functional visualization diagnostics has acquired the substantial significance in diagnostics, especially in case of focal epilepsy. In an increasing number of cases by means of the enhanced magnetic resonance imaging scanners it has become possible to detect the potential reason of the focal epilepsy which is mapped as an affected area during the MRI procedure.  The post-processing methods can increase the sensitivity of this detection also in such difficult cases for diagnosis as the structural damage of cerebral cortex. The functional visualization methods which register the metabolic activity or the brain blood circulation between or during the epileptic seizures help to elicit even more essential features of epileptic focus localization. The functional magnetic resonance imaging gives additional important information about the functionally significant brain areas.

In Freiburg in the Department of Neuroradiology as well as in the Department of Medical Physics there are 3T-MRI scanners for the structural and functional high-resolution magnetic resonance imaging. The research of brain functions among the patients with epilepsy is made in cooperation with the Department of Nuclear Medicine.

MRI in the Department of Neuroradiology

MRI in the Department of Neuroradiology

SPECT-camera

SPECT-camera (Single Photon Emission Computed Tomography) for the measurement of functional parameters between and during the epileptic seizures in the Department of Stereotactic Neurological Surgery

Sensitive detection of the moderate changes of hippocamp (Department of Medical Physics)

Sensitive detection of the moderate changes of hippocamp (Department of Medical Physics)

Detection of neuronal migration abnormality (cortical dysplasia) Department of Neuroradiology

Detection of neuronal migration abnormality (cortical dysplasia) Department of Neuroradiology

MR-postprocessing: Voxel-based image of cortical and cerebral turbidity

MR-postprocessing: Voxel-based image of cortical and cerebral turbidity

The image of electrode grid position made by means of curvilinear reformatting

The image of electrode grid position made by means of curvilinear reformatting

Ictal hyperperfusion in SPECT in case of cryptogenic frontal focal-cortical dysplasia (Department of Nuclear Medicine)

Ictal hyperperfusion in SPECT in case of cryptogenic frontal focal-cortical dysplasia (Department of Nuclear Medicine)

FDG-PET for hypometabolic area detection (here: focal-cortical dysplasia in the frontal part on the left side) (Department of Nuclear Medicine)

FDG-PET for hypometabolic area detection (here: focal-cortical dysplasia in the frontal part on the left side) (Department of Nuclear Medicine)