@ iStock

Timely intervention by a professor at the Medical Center - University of Freiburg helped save the leg of a patient with a rare immune disorder and avoid amputation.

Fatma B.*, a 41-year-old woman, suffers from a rare genetic disorder – NFkB1 gene deficiency. This condition weakens her immune system and triggers autoimmune reactions. Regular injections of a carefully tailored combination drug are essential for her survival.
In recent years, Fatma has been under the care of Professor Dr. Bodo Grimbacher, Deputy Director of the Center for Chronic Immunodeficiency (CCI) at the Medical Center - University  of Freiburg. "Our patients’ lives often depend on individually developed combinations of treatment methods and medications. Any interruption in therapy can be life-threatening," explains the professor.

Diagnosis and Assistance from Afar: Treatment Began in Turkey

During the Christmas holidays, Fatma traveled to Turkey to visit her family. Shortly before her return to Germany, open wounds appeared on her leg, worsening rapidly within a day. Doctors at a local Turkish clinic, unfamiliar with such a condition, were at a loss. Amputation seemed inevitable. In desperation, Fatma contacted Professor Grimbacher, who prescribed anti-TNF antibody therapy and a critical injection over the phone. "In such cases, time is of the essence," emphasizes the doctor. "We had to act quickly to save her leg."

Treatment Took Effect the Next Day

A friend of the patient promptly delivered the necessary medication to Turkey. The treatment showed results the very next day: the wound's progression was halted. Fatma spent several weeks in the hospital until her condition stabilized, allowing her to return to Germany for further care.

Back in Freiburg: Leg Saved

Upon her return to Freiburg, Fatma was hospitalized at the Medical Center – University of Freiburg for another two weeks of inpatient treatment. Her leg was saved, and professional care helped restore her health. "I am endlessly grateful to the doctors and everyone who helped me," she says. Fatma now eagerly looks forward to reuniting with her family while always remembering the importance of carrying her life-saving medication.

*Name changed